The United States launched nearly five dozen cruise missiles at a Syrian airfield early Friday in response to a chemical weapons attack that killed dozens of civilians, the first direct assault on the Damascus government since the beginning of that country’s bloody civil war in 2011.

“It is in the vital national security interest of the United States to prevent and deter the spread and use of deadly chemical weapons,” President Donald Trump said in a statement. “Tonight I call on all civilized nations to join us in seeking to end the slaughter and bloodshed in Syria, and also to end terrorism of all kinds and all types.”

Fifty-nine Tomahawk missiles targeted an airbase at Shayrat, located outside Homs. The missiles targeted the base’s airstrips, hangars, control tower and ammunition areas, officials said.

Pentagon spokesman Capt. Jeff Davis said initial indications were that the strike had “severely damaged or destroyed Syrian aircraft and support infrastructure and equipment … reducing the Syrian Government’s ability to deliver chemical weapons.” There was no immediate word about any casualties.

Trump said the base was used as the staging point for Tuesday’s chemical weapons attack on rebel-held territory, which killed as many as 72 civilians, including women and children.

“Assad choked out the lives of helpless men, women and children,” Trump said from Mar-a-Lago, Fla. “Even beautiful babies were cruelly murdered in this very barbaric attack. No child of God should ever suffer such horror.”

National Security Adviser H.R. McMaster said the strike should cause a “big shift in Assad’s calculus.”

“Obviously the regime maintains a certain capability to commit mass murder with chemical weapons beyond this air field,” McMaster said. “But it was aimed at this airfield because we could trace that attack back to this facility. It was not a small strike.”

The U.S. missiles hit at 8:45 p.m. Eastern time, 3:45 a.m. Friday morning in Syria. Syrian state TV called the attack an “aggression” that lead to “losses.”

U.S. military officials said they informed their Russian counterparts of the impending attack in an effort to avoid any accident involving Russian forces. Nevertheless, Russia’s Deputy U.N. ambassador Vladimir Safronkov warned that any negative consequences from the strikes would be on the “shoulders of those who initiated such a doubtful and tragic enterprise.”

Davis, the Pentagon spokesman, confirmed that “there are Russians at the base,” but said they had been warned “multiple times” to leave. He did not know whether Russian aircraft were at the base when the missiles hit.

The U.S. also notified its partner countries in the region prior to launching the strikes.

U.S. defense officials tell Fox News that two warships based in the eastern Mediterranean, the USS Porter and the USS Ross, have been training for the past two days to execute this mission.

“Our forward deployed ships give us the capability to quickly respond to threats,” said a Navy official. “These strikes in Syria are a perfect example – this is why we’re there.”

The original plans called for two targets, the airbase and a chemical weapons storage facility. However, Pentagon planners decided late Thursday to target just the airbase.

As a candidate, Trump warned against against the U.S. getting pulled into the Syrian civil war. But the president earlier in the week appeared moved by the photos of children killed in the chemical attack.

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Evangelist Dina Amelia Kalmeta is the Founder and CEO of Your New Life in Christ Ministries - CWW7NEWS. Evangelist Dina reports on world events as they pertain to Bible Prophecy. Before Your New Life in Christ Ministries, Evangelist Dina served as a Leader for INCHRIST NETWORK leading teams online and spreading the Gospel of Jesus Christ. Her mission today is to bring hard evidence that what is taking place in the world isn't just coincidence, but indeed proof that the last days the Bible warned us about are upon us right now.